Automated ETDRS: Defocus Curve

CTS from M&S is a fully-automated suite of protocols that can be customized for any study.

Key Features of the Automated ETDRS: Defocus Curve

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Defocus Curve automates ETDRS testing from the standard +2.0 diopters through -5.0 but is customizable depending on specific study requirements
Diopters from +0.5 to -0.5 decrease in .25 increments to be in compliance with FDA suggestions
Automated algorithm quickly and accurately measures visual acuity while eliminating technician bias and erroneous results
Choose Sloan letters (10) or British Standard Institution letters (12)
The system randomizes each presentation thereby eliminating the memorization effect and is consistent and repeatable
Utilizes an infinite number of chart randomizations throughout the protocol
System calibration is set in meters at virtually any distance and is adjustable and precise to within 1 cm
The system is calibrated for both distance-to-subject and pixels-per-inch so that optotypes precisely follow ANSI Z80.21-2020 and ISO 8596:2017 in regard to size, spacing between optotypes, and spacing between lines
Background luminance is carefully calibrated to 85 cd/m2 for standardized ANSI and ISO testing or any other background luminance from 80 to 320 cd/m2 or as required for a study
ETDRS results indicate ETDRS numerical score, visual acuity level and log value
Test results can be exported to any media file in any format for statistical analysis
Peer-reviewed and validated to existing ETDRS standards by Southern College of Optometry, August 2015

The system is controlled by a high-resolution tablet via a standard Bluetooth connection utilizing our CustomLink® technology
The testing mechanism interfaces seamlessly with CTS (Clinical Trial Suite) to allow the technician to follow the protocol as determined by the sponsor
At the beginning of the test the technician is prompted to insert a certain diopter trial lens
A descending ETDRS logMAR chart is presented using either ten Sloan letters or twelve British Standard Institution letters
The subject responds with the smallest line where all five letters can be correctly read and the technician simply enters the line number and presses “Submit”
The chart then randomizes, setting the selected line to the top line and a pointer is shown at the next smaller line
The subject is then asked to read this line, and the number of correct letters is input; the pointer moves to the next line and so on until the subject is no longer able to identify any correct optotypes on a line
The technician is then prompted to change the trial lens to the next lens in the sequence
When the test is complete the results are reported in the standard ETDRS Letter Score, Visual Acuity equivalent and logMAR equivalent

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